Human Sera
Cayman Chemical R-Lnsoprazole 50mg
A cell permeable phenoxazine derivative that suppresses IGF-1-stimulated phosphorylation of Akt with an IC50 value of 1-2 M inhibits the growth of Rh1 Rh18 and Rh30 cells with IC50 values of 2-5 M
Cayman Chemical TrIamcInolon acetonIde 100mg
An orally active direct inhibitor of Factor Xa (Ki 0.4 nM) that inhibits thrombin formation without prolonging bleeding time approved for clinical use as an anticoagulant in the prevention of stroke and the treatment of venous thromboembolisms
Cayman Chemical DIgItoxIgenIn 50mg
Immunogen Synthetic peptide from the C-terminal region of human MBOAT5 Host Rabbit Species Reactivity ( ) Human Applications FC and IF
Cayman Chemical BetaxololhydrochlorIde 50mg
Immunogen Purified ovine COX-1 Host Mouse Species Reactivity ( ) Human mouse rat bovine (-) Other species not tested Cross Reactivity ( ) Human ovine COX-2 (-) Mouse COX-2 Applications IHC WB
Cayman Chemical MonbromobImn 100mg
A lipophilic electrophile that has profound effects on oxidative and immunological pathways activates the transcription factor Nrf2 resulting in heme oxygenase-1 expression and increased glutathione levels suppresses the expression of pro-inflammatory cytokines and inhibits angiogenesis
Cayman Chemical ClInafloxacInhydroCLOrID 100mg
A tetrachloro indandione that acts as a potent inhibitor of UCH-L3 and demonstrates 125-fold selectivity over UCH-L1 (IC50s 0.6 and 75 UM respectively)
Cayman Chemical FexofenadInhydrochlorIde 100mg
An irreversible inhibitor of mutant forms of EGFR including T790M (Ki 21.5 nM) with minimal activity at the wild-type EGFR (Ki 303.3 nM) inhibits the proliferation of NSCLC cells expressing mutant EGFR (GI50s 7-32 nM) and demonstrates anti-tumor activity in NSCLC EGFR mutant xenograft and transgenic models
Cayman Chemical MozavaptnhydrochlorIde 100mg
A substrate for the synthesis of RNA during the transcription process and the synthesis of DNA during DNA replication participates in G-protein-related signal transduction where it is converted to GDP through the action of GTPases
Cayman Chemical 3hydroxy3MethylglutarIc n 50mg
A monohydroxylated metabolite of AB-CHMINACA intended for forensic and research applications
Cayman Chemical AdenosIn 5-dIphosphate 100mg
An allosteric agonist of the CaSR (EC50 79.4 nM in HEK293T cells expressing the human receptor) decreases plasma levels of PTH in rats from 0.1-10 mg/kg decreases plasma levels of PTH and parathyroid cell proliferation in a mouse model of primary hyperparathyroidism
Cayman Chemical OrbIfloxacIn 100mg
A cell-permeable non-steroidal antagonist of the estrogen receptor GPER (Ki 20 nM) displays low affinity cross-reactivity with the classical estrogen receptor ERa so that at doses greater than 1 UM it is capable of mediating limited ER-dependent transcriptional activity
Cayman Chemical 2Chloro4nItrophenylaDgl 100mg
A dopamine receptor antagonist (Kis 2.4 0.3 and 1.8 nM for D2 D3 and D4 receptors respectively) binds to eight additional receptors (Kds 25-3100 nM for the human receptors) and inhibits Nav1.2 and Kv11.1 (IC50s 42 and 340 nM respectively) decreases the number of licks and reduces fluid intake of a sweetened solution in rats at 0.5 1 and 2 mg/kg decreases the number of attacks and threats and increases immobility time in the neutral arena aggression test indicating increased passiveness in male mice at 0.75 mg/kg for 10 days
Cayman Chemical TrImetazIdInhydrochlorIde 50mg
An antagonist of MDM2 that suppresses the growth of cancer cell lines expressing wild-type p53 (IC50 values range from 240-440 nM) orally bioavailable having anti-proliferation as well as apoptotic actions in various tumor models affects multiple signaling pathways
Cayman Chemical EnalaprIlathydrate 100mg
RORY Reporter Cells are prepared using INDIGOs proprietary CryoMite process. This cryo-preservation method yields high cell viability post-thaw and provides the convenience of immediately dispensing healthy division-competent reporter cells into assay plates. There is no need for intermediate spin-and-wash steps viability determinations or cell titer adjustments. [INDIGO Catalog Nos. IB04001-32 IB04001 IB04002]
Cayman Chemical 7-MethylgunIn 50mg
A reversible inhibitor of serine proteases such as trypsin (Ki 0.06 pM) chymotrypsin (Ki 9.5 nM) and kallikrein (Ki 0.8 nM) widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest